Published December 7, 2016
The Bill and Melinda Gates Foundation has awarded a $1.1 million grant to the University of Colorado at Boulder to develop next-generation vaccines that do not need to be refrigerated. The money will fund research conducted by Robert Garcea, PhD, Theodore Randolph, PhD, and Alan Weimer, PhD, who work in the university's Jennie Smoly Caruthers Biotechnology Building (JSCBB). A major goal is to develop genetically engineered vaccines that deliver time-released doses in the body. Dr. Garcea, who is with the Department of Molecular, Cellular and Developmental Biology and the BioFrontiers Institute, has teamed up with Dr. Randolph and Dr. Weimer of the Department of Chemical and Biological Engineering.
Published December 6, 2016
The World Health Organization (WHO) defines a vaccine as a "biological preparation that improves immunity to a particular disease." The WHO further states that a vaccine "typically contains an agent that resembles a disease-causing microorganism" and that it is "often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins." The idea is for the weakened or killed microbes to stimulate the "body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters."