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Tdap Vaccinations for All Pregnant Women in Brazil Mandated in Late 2014

In October 2014, the Brazilian Ministry of Health’s Epidemiological Surveillance Center “Prof. Alexandre Vranjac” (CVE) in São Paulo, Brazil published a “technical report” on the diphtheria, tetanus and pertussis vaccine (Tdap).1 In that report, the CVE stated that the Tdap vaccine would be included in Brazil’s National Vaccination Schedule for pregnant women.

Considering the epidemiological situation of the [pertussis] disease and the need to protect the mother-child pair, the Tdap vaccine will be incorporated into the National Vaccination Schedule for pregnant women and health professionals (anesthesiologist, gynecologist, obstetrician, neonatologist, pediatrician, nurse, and nursing technician) who care for newborns in maternity wards and nurseries/neonatal ICUs.1 

A retrospective study published in the journal BMC Infectious Diseases in 2015 highlights the growing incidence of pertussis (whooping cough) in Brazil from 2007 to 2014. Using data obtained from case notification forms, the study identified a total of 80,068 “suspected cases” of pertussis in Brazil during that seven-year period.2 Another study published in Autopsy Case Reports last year cited the increasing number of deaths from pertussis in Brazil in recent years, particularly in 2013.3

In 2013, 109 pertussis-related deaths were reported—a number 7-fold higher than the average number of deaths reported annually in the period from 2001 to 2010. More than 80% of the deaths occurred in infants younger than 3 months of age.3

It is understandable that the Brazilian government was concerned about the upward trend in pertussis infections. By the end of 2014, following the October report from the CVE, the Brazilian Ministry of Health announced the introduction of the Tdap vaccine for all pregnant women in the country,3 and the Brazilian National Immunization Program (NIP) had begun the vaccinations.2

(In 2011, with little evidence proving safety, the CDC instituted a similar universal use Tdap vaccine policy for all pregnant women in the U.S. in an attempt to control pertussis infections)4

The policy change to vaccinating pregnant women with Tdap to try to control pertussis infections in Brazil had been expected for many months. Earlier in 2014, at a meeting of the World Health Organization’s (WHO) Strategic Advisory Group of Experts (SAGE), the group had written in a background paper…

[Brazil] will recommend Tdap in the routine immunization programme for pregnant women from 2014 onward.5 .

The CVE report recommended the Tdap vaccine be given to women between the 27th week and 36th week of their pregnancy, and that it could also be administered up to 20 days prior to the expected date of birth.1 The report specified the Tdap produced by GlaxoSmithKline (GSK) of the United Kingdom as the one to be used. GSK has a technology transfer agreement with Brazil’s Butantan Institute for the production of the Tdap vaccine6 in Brazil.

The CVE report listed the following ingredients in the GSK/Butantan Institute Tdap vaccine:

  • Diphtheria toxoid—not less than 2 International Units (IU)
  • Tetanus toxoid—not less than 20 International Units (IU)
  • Bordetella pertussis antigen
  • Pertussis toxoid—8 mcg
  • Filamentous haemagglutinin—8 mcg
  • Pertactin—2.5 mcg
  • Adsorbed hydrated aluminum hydroxide (Al (OH ) 3) and aluminum phosphate (AlPO4)
  • Excipients: aluminum hydroxide , aluminum phosphate , sodium chloride and water for injection. Contains formaldehyde residues, polysorbate 80 and glycine1

GSK’s Tdap product is internationally known under the brand name Refortrix® or, more commonly, Boostrix®), and it has been licensed in Brazil for more than a decade.7 In addition to the ingredients listed above for Boostrix, the following growth medium and process ingredients are used in manufacturing the vaccine:

  • modified Latham medium derived from bovine casein
  • Fenton medium containing bovine extract
  • formaldehyde
  • Stainer-Scholte liquid medium
  • glutaraldehyde
  • aluminum hydroxide8

According to GSK, neither the safety nor effectiveness of Boostrix have been established in pregnant women.8 The package insert for Boostrix reads:

A developmental toxicity study has been performed in female rats at a dose approximately 40 times the human dose (on a mL/kg basis) and revealed no evidence of harm to the fetus due to BOOSTRIX. Animal fertility studies have not been conducted with BOOSTRIX. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, BOOSTRIX should be given to a pregnant woman only if clearly needed.9

Despite this cautionary information, the Brazilian government has been vaccinating tens of thousands, if not hundreds of thousands, of pregnant women in its country during the past year. A large portion of these pregnancies are occurring in Brazil’s northeastern region, notably in the state of Pernambuco—the country’s fastest growing population center.10 11


References:

1 Centro de Vigilância Epidemiológica “Prof. Alexandre Vranjac” (CVE). INFORME TÉCNICO–VACINA DIFTERIA, TÉTANO E COQUELUCHE (dTpa). cve.saude.sp.gov.br October 2014.
2 Guimarães LM, Neves da Costa Carneiro EL, Carvalho-Costa FA. Increasing incidence of pertussis in Brazil: a retrospective study using surveillance dataBMC Infect Dis 2015; 15: 442.
3 Palazzi Sáfadi MA. Pertussis in young infants: a severe vaccine-preventable diseaseAutops Case Rep April-June 2015; 5(2): 1-4.
4 Fisher BL. Vaccination During Pregnancy: Is It Safe? NVIC Newsletter Nov. 9, 2013.
5 World Health Organization (WHO). WHO SAGE pertussis working group: Background paper, SAGE April 2014. WHO.int April 2014.
6 Instituto Butantan. vaccines. Butantan.gov.br.
7 de Carvalho AP, Pereira EMC. Acellular pertussis vaccines for adolescentsJ Pediatr July 2000; 82(3).
8 Vaccine Ingredients and Manufacturer Information. CarProCon.org
9 GlaxoSmithKline (GSK). Package Insert for Boosterix. us.GSK.com
10 Bevins V. Brazil’s historically poor northeast finally gets its boom. Los Angeles Times May 24, 2012.
11 Sells H. Brazil’s Northeast Emerging as Economic Powerhouse. CBN News July 23, 2012.

40 Responses

  1. Dear Sir/Madam,

    How likely that Zika is a result of those vaccinations; if so, should not a legal challenge be mounted. it’s a crime against those women.

    Best

    1. Tdap has nothing to do with the Zika virus. As everyone should know, the Zika virus is actually a product of Russell’s Teapot overflowing and drenching parts of Africa. The timing is right.

      1. Since no actual long term studies on most vaccines has been done, no studies with control groups, and most vaccines clearly state on the inserts that there have been NO studies on pregnant women how can anyone say this is not related? The birth defect seen in these babies is microcephaly which IS documented as a condition that can be caused by dtap!

        Read the package inserts before you consent to any vaccine! Those can be found through the following link as well as very helpful info:

        http://www.stopmandatoryvaccination.com/vaccine-dangers/

        1. There is a difference between the DTaP and the TDaP. DTaP is given at 2, 4, 6 and 15 months of age. Tdap is given to adults and has been in the US for the past 10 years or so with no increase in microcephaly rate.

          1. Hi to all:

            Yes. correct no side-effects in the States, but only yes to ADULT, not to pregnant women !!!
            Side-effects among others may be Guillain-Barré-Syndrom !!
            (Information by GSK in the Boostrix package insert)
            GBS known in adults, what may happen to an embryo?
            No human data available about application of Boostrix during pregnancy

            (German: Es sind keine Humandaten aus prospektiven klinischen Prüfungen zur Anwendung von Boostrix während der
            Schwangerschaft verfügbar)

          2. Jane, there may not been an increase in the U.S. because we have access to ultrasound that would find the defect before a baby is born. I think it would be safe to believe that the parents would be given the option for an abortion once their doctor provide them with the information regarding the condition and the likely outcome. I am not sure if ultrasound is a regular option in Brazil or what their abortion laws are. This could account for the increase of microcephaly if the Tdap/Dtap etc. is the cause.

            There are of course a lot of other variables that must be considered before Zika can be claimed as the main cause. I read an article regarding deaths of microcephalic infants in Brazil. For example, out of 49 infant deaths “expected” to be caused by Zika only 5 had it in their brains, something else was the cause, so what was it? The government and the WHO may be using Zika as a cover for Tdap/Dtap etc. I think it would be pertinent to consider that this might be the case.

    2. The problem is not Zika. The problem is Microcephaly which may have been caused by such program. Brazilian Government tries to blame it on Zika, saying that the 4400 cases are “suspected” to be caused by ZIKV.

      Meanwhile, no cientis could find a real, concrete and definitive proof that Zika causes Microcephaly. Since I doubt they will ever find it, it seems to me that the diverson campaign led by Dilma’s Cabinet is worthy a Crime Against Humanity indictment!

  2. The Zika virus is being blamed for the birth defects showing in babies born in Brazil, but apparently, the Zika virus is not showing up in all babies born with microcephaly (small heads and brains). The commonality is the dTap vaccine taken by these women during pregnancy. Zika virus has been around since about 1940, I have read, and its a mild virus.

  3. it’s a strange coincidence – when they started to administer these vaccines, their pregnant women have now problems with Zika virus. Zika virus didn’t just appear last year, it existed long before, So why now they have all these issues? something to think about.

    1. The zika virus existed — in Uganda. It is postulated that the zika virus arrived in Brazil from Africa last April by way of French Polinesia, and began this pandemic.

  4. I would like to know what brand of Tdap vaccine the US and other countries have been using for pregnant women and if our rates of microcephaly have also risen. I know that we have many cases of it annually. This and the use of pesticides, manufacturing of pesticides, use of GE mosquitoes and the desperate poverty and poor nutritional status of the women in Brazil giving birth to brain damaged babies should be where all the world’s efforts should be. Certainly not in handing out more toxins in the form of mosquito spray or releasing yet more untested GE mosquitoes.

  5. Let’s see – mosquito since time immemorial…
    vaccines since about 100 years…

    God made the mosquito and man gave us vaccines…

    God = Good
    Man = Madness

    Got it? This is not rocket science…

  6. Just curious…I have read several sources saying the Tdap program was initiated in May 2015…which would make the many birth defects reported by November 2015 seem much more likely as a result of Tdap than if it was initiated in October. Sometimes there is such conflicting information it is difficult to keep things straight and form an educated opinion/decision. Did this start in May or in October? Seems significant if we’re going to point to Tdap as the cause….

    Thank you!

  7. Recent studies independent of Big Pharma have shown that the DTaP vaccine has caused the mutation of the pertussis virus into more virulent strains, such as parapertussis, against which the DTaP is powerless. Most likely this kind of microbe mutation is being caused by all live viral vaccines. In any case, recent outbreaks of pertussis in the U.S. have been among heavily or totally vaccinated populations. Mandating the DTaP for pregnant women is just another facet of the economically driven vaccine policy that, whether by accident or intention, is slowly but inexorably genocidal.

    1. Whooping cough is caused by a bacteria. The ineffectiveness of the vaccine is likely due to the lack of localized immune response in the lungs themselves, and also that fact the immunity wears off quite quickly compared to wild immunity. It has nothing to do with a viral mutation.

    1. Children should not be vcaicnated. After years of suffering sickness from vaccinations, I havent been sick once since I stopped taking them. My step son had a 4.0gpa and had perfect attendance intel he took the whooping cough, he was terriably sick for two weeks for something he MIGHT get. No more 4.0 and perfect attendance this year. Feed your kids healthy food, pently of vitiams and exersize and they will never get sick.

  8. Does ANYBODY remember the morning sickness pill THALIDOMINE???????? This is nothing new. vaccines given to pregnant women is unsafe.

  9. Article forgot to mention that the rat studies done by GSK on the TDaP (Boostrix) did NOT use an inert placebo, but instead used another vaccine – so they found little difference in adverse reactions BETWEEN THE TWO VACCINES. Probably would have been a much different story if they’d actually used an inert placebo which is the gold standard of scientific testing, which honest scientists who have nothing to hide would have used.

    Source? Take a look at the vaccine package insert for TDaP (Boostrix). It’s easy enough to find, but you might get harassed by your doctor if you should dare ask them to show it to you. Don’t let them foist the 1 page summary sheet off on you – insist on the actual vaccine package insert from the manufacturer.

    1. Nowhere does it provide edcevnie that vaccines are ineffective throughout history. It is difficult to prove a negative but how about this. Vaccination programs in the late 19th and early 20th century decimated the populations of many countries where government sponsored vaccination programs were introduced. Japan suffered 48,000 deaths from smallpox vaccination; England and Wales experienced 45,800 smallpox deaths in a population that was 97% vaccinated against smallpox. Australia and Germany combined with a total of 120,000 deaths from the very smallpox for which they had been vaccinated. European deaths amongst the vaccinated portion of the population totaled 3,000,000. Deaths from smallpox vaccination programs began to decline when a revolt against mandatory vaccination programs emerged from the chaos. Within twenty years mandatory smallpox vaccination laws in England were repealed. In 1919 the death rate from smallpox promptly plummeted to a total of 28 deaths in a population of almost 40,000,000 people. Previously, with mandatory vaccinations they had averaged over 44,000 deaths from smallpox. Vaccination History A huge outcry amongst the public ensued Over 100 union parished ripped up the local vaccination ordinances in 1872, and instead called in the Sanitary engineers, and started putting in sewage disposal plans, rubbish dispose, proper corpse disposal and jointed pipes to ensure uncontaminated water. Those were the measures officially adopted under the Public Health Act in 1875. the offical records states that those parishes were the ones that by and large escaped the 1878 smallpox epidemic. In 1871-2, England, with 98% of the population aged between 2 and 50 vaccinated against smallpox, it experienced its worst ever smallpox outbreak with 45,000 deaths. During the same period in Germany, with a vaccination rate of 96%, there were over 125,000 deaths from smallpox. The Hadwen Documents In 1862, Anglican church missionaries Rev. John Sheepshanks and Robert Brown inoculated interior Salish Indians in B.C. with a live smallpox virus that wiped out entire native communities within a month, just prior to the settlement of this native land by gold prospectors associated with these missionaries and government officials. Canadian Genocide by Vaccination By 1853, Parliament began passing laws to make the untested vaccine compulsory throughout the British Empire. Other countries of Europe followed suit. Once the economic implications of compulsory vaccinations were realized, few dared to disagree. Then, as now, the media were controlled by the vaccine manufacturers and the government, who stood to make huge money from the sale of these spurious vaccines Tim O’Shea, D.C.“In 1853 England introduced compulsory vaccination. Before this time the highest death rate from smallpox was 2000 for any two year period. However 20 years later there were 23,062 deaths in England and Wales with smallpox spreading over Europe in all the countries where vaccination was practiced on a large scale. During the same epidemic in Germany 124,948 people died of smallpox. Of the 155 persons admitted to the Smallpox Hospital in the Parish of St. James, Piccadilly, 145 had been vaccinated.” Doctor Phillip Incao MD

  10. ALL vaccinations contain dangerous ingredients which are clearly meant to do great harm. Pregnant women should never be given any vaccinations because of the potential great harm to their unborn children.

    Tdap vaccinations strongly appear to have produced babies with severe head and brain damage. I fervently hope the parents will file class action lawsuits against the vaccine manufacturer.

    No one should ever be required to take a single vaccination. No one.

    VACCINATIONS are a WICKED CRIME AGAINST HUMANITY.

    1. Lauren Thanks for sharing the CHOP Tdap sheet.OB/Gyn’s do a great job of gnttieg post-partum moms vaccinated, but the public health campaign fails to reach dads and grandparents, who are often around newborns just as much and put them at grave risk. I stress the importance of this vaccine to parents at the newborn visit, especially after seeing a 2-month-old die from Pertussis as a resident. The problem is that many of my patient’s parents do not have insurance and their access to care limits them from easily gnttieg this vaccine. With the epidemic numbers of pertussis that we are seeing, especially in states like Vermont and Washington, where immunization rates are low, we should be thinking of creative solutions to reaching these parents and grandparents in accessible and affordable ways.

  11. Isn’t it curious how with such a plethora of conflicting scientific data out there that the media has not given e-q-u-a-l coverage to both sides of vaccination argument? Have they been given a directive that it is to say it is not a worthy debate to publicize ‘unfounded’ science or that the public doesn’t want to hear about that kind of ‘stuff’? Or is it that the pharmaceutical companies who pay well for advertisements will pull their funding if the debate ever occurs on any well known media site/station? Are they afraid the public might start researching and advocating for themselves instead of blindly following orders? Why were the pharmaceutical companies given ‘immunity’ from many vaccination lawsuits decades ago? Why are they so above the laws we must follow? By mandating these immunizations they are removing our freedom to think for ourselves. Perhaps I am not well versed in scientific matters but I can learn much from reading and studying. You don’t need a degree to see that there is something wrong with the way some of our world’s leaders are mandating such dangerous vaccination protocols. Especially on vaccinations that are fast tract. What is even more disturbing are the commercials on medications with their messages of horrifying side affects blatantly marketed with happy smiling faces. Have we become so complacent a society that we don’t want to be bothered in using our brain or are we afraid to have a difference of opinion and be shunned from the majority of society who just don’t see the point in making a fuss over things that don’t affect “me”? I’m sure over time I will find a variety of answers to sift through….but that’s how we make important well thought out decisions that may affect ourselves and our future generations.

  12. Multiple variables. First hing to do is remove ZIKA from the equation. that’s just a misdirection, a cover story made up by the CDC’s little-known Epidemic Intelligence Service (EIS). Basically it’s the office of disinformation.

    According to Jon Rapport:
    Graduates of this EIS program, as proudly stated by the CDC, have gone on to occupy key positions in the overall medical cartel: Surgeons General; CDC directors; medical school deans and professors; medical foundation executives; drug-company and insurance executives; state health officials; medical editors and reporters in media outlets.

    It’s a loyal insider’s club. They collaborate to float prime-cut, A-number-one cover stories of extraordinary dimensions. They invent medical reality out of thin air.

    Zika has been around for 70 years and none of the documented data states births defects or it being transmitted sexually as the WHO is putting out in the media. People who have documented cases, 1 person in 5, have no more than a mild upper respiratory illness like a flu. This is a ruse, a flim flam, a distraction-a cover-up to keep the Herd immobilized in fear, eating up every single lie that the media puts out. Some of the things they don’t want people around the world to know:

    -The Gates Foundation, around 2011-2012 funded and release GM mosquitoes to “combat” Dengue fever in the epic center of this fake epidemic.

    -Brazil, epicenter of the Zika crisis, uses more pesticides than any nation in the world. Most of the chemical are banned in other countries. And as for babies born with smaller heads, here is a study from
    *Environmental Health Perspectives (July 1, 2011), Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort*.
    Atrazine and metolachlor, the biomarkers in this study are both used in Brazil.

    -The TdaP vaccine became mandatory for pregnant women in 2014 despite the fact it has never been tested on pregnant women.

    -Pesticides are made in Brazil and a prosecutor is suing corporation for violation of safety codes because the manufacturing of these pesticides are releasing dangerous toxins into the environment.

    -Factor in poor nutrition, severe and endemic malnutrition, lack of basic sanitation, and grinding poverty.

    -Use of mosquito spray-aerial & topical.

    All of the above —A Recipe For Disaster!

    What you have here is a COVERUP involving the Brazilian Government/The company releasing the GE mosquitoes, Oxitec, has grants for their experiments from Bill Gates—(never a good sign)/Oxitec is owned by Intrexon, which is owned by billionaire Randal J Kirk/WHO/GVSI/Task force For Global Health–all the major players involved in depopulation.

    Additional information:
    Canadian scientist Gary Kobinger, part of a consortium working on the vaccine, told Reuters in an interview that the first stage of testing on humans could begin as early as August.
    If successful, that may allow the vaccine to be used during a public health emergency, in October or November: http://www.dailymail(dot)co.uk/health/article-3422951/Zika-vaccine-ready-OCTOBER-Researchers-claim-experimental-vaccine-easy-produce-given-ahead-public-health-emergency.html#newcomment.

    Wow-talking about Fast tracking a drug. Hmmm, this makes one think that this drug was just sitting on a shelf somewhere. A vaccine for a virus that has been characterized by medical literature as mild and has no history of birth defects.

    The Virus itself is speculated to be man made because it was discovered by scientist that workes for the Rockefeller Foundation (never a good sign). You can actually buy it online (ZIKA).
    The Deadly Zika Virus is Available For Sale Online, Courtesy of the Rockefeller Foundation
    Read more at http://thefreethoughtproject(dot)com/?s=zika#YT634IX5WxP8OORl.99

  13. Just speculating here but is there a pattern that’s being overlooked? A mosquito bite is not causing an epidemic of Microcephalophis. I believe it is a combination of co factors and pesticides being at the top of the list. What has been overlooked is this:

    -Seven cases of a rare fatal birth defect were reported in a remote region of Washington state in 2013, making it the fourth consecutive year that rates have more than tripled the national average, health officials said Tuesday.

    There’s still no clear reason for the spike in anencephaly, a severe defect in which babies are born missing parts of the brain or skull, according to Washington state health officials. NBC News investigated the issue in February.

    But it brings to 30 the number of cases reported since 2010 in the area that includes Yakima, Benton and Franklin counties in central Washington state. The anencephaly rate jumped to 8.7 cases per 10,000 births in the region, far exceeding the national rate of 2.1 cases per 10,000 births.

    “We’re really concerned about the fact that the anencephaly rates are still so high,” said Mandy Stahre, an Epidemic Intelligence Service officer with the Centers for Disease Control and Prevention based in Washington state. “We were sort of hoping that this may have been a statistical anomaly or would go away.”
    Rare Birth Defects Still Spiking in Washington State: http://www.nbcnews(dot)com/health/health-news/rare-birth-defects-still-spiking-washington-state-n86916.

    What both of these tragedies have in common is :PESTICIDES.

    As of the end of 2015 there are 40 documented cases between 2010-2015.

  14. A woman in Hawaii gave birth to a baby in January of this year with microcephaly. She had lived in Brazil up until May, 2015. She would have been one month into her pregnancy when she left Brazil, so she wouldn’t have received the vaccine. I originally thought the vaccine was the culprit, but now I’m not so sure. I think it’s more complicated. Any thoughts?

    1. Tdap vaccine during pregnancy. People who have been vaccinated, including the Tdap or Dtap, shedding the diseases for which they were vaccinated. GMO mosquitoes. Heaps of pesticides that are rejected elsewhere in the world. What could possibly go wrong?

    2. Just note that if you choose for your child to not reeecvid the Tdap vaccine that they will be excluded from school if there is an outbreak of the disease. Pertussis (whooping cough) has been going around and is the reason that the State of California is requiring the booster. There are people have died from whooping cough.

  15. for Keith and his question about the woman in Hawaii: in Hawai they also advice the DTaP shot to pregnant women :

    https://www.hawaii.edu/medicine/pediatrics/pedtext/s01c04.html:
    copy from website

    ” The exception that pregnant women receive a Tdap booster dose at 20-weeks gestation or later during that pregnancy and for all subsequent pregnancies in order to protect the unborn infant from acquiring pertussis prior to receiving the primary series in infancy beginning at 2 months and from

    another website Hawai news (http://health.hawaii.gov/docd/files/2013/07/VFC_NewsOctober2011.pdf):

    ” Is it true that tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is now recommended for pregnant women?
    Yes! The Advisory Committee on Immunization Practices (ACIP) approved recommendations for the use of Tdap vaccine for pregnant women in June 2011.
    Health care providers should administer Tdap during pregnancy, preferably during the third or late second trimester (after 20 weeks gestation) for pregnant women who have not previously received Tdap. If not administered during pregnancy, Tdap should be administered immediately postpartum. Also of note, a recent study found that pediatricians are a key source of information for pregnant women regarding Tdap vaccine.”

  16. I just wanted to point out that I was given the tdap vaccine while I was pregnant and my son was born with microcephaly the doctors did not tell me he had microcephaly when I received my sonogram we have had genetic testing done so we did not get it from it me or his father I believe it was the vaccine

  17. My heart goes out to the indigenous people of Brazil that are STILL, to this day being subjected to these sick bouts of GENOCIDE!!! Where are the organizations that are supposed to PROTECT them from such atrocities!?!??

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